THIS PAPER DOCUMENT IS BEING SUBMITTED PURSUANT TO RULE 901 (d) OF REGULATION S-T UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* Gilead Sciences, Inc. (Name of Issuer) Common Stock, Par Value $ .001 per share (Title of Class of Securities) 375558103 (CUSIP Number) Check the following box if a fee is being paid with this statement . (A fee is not required only if the filing person: (1) has a previous statement on file reporting beneficial ownership of more than five percent of the class of securities described in Item 1; and (2) has filed no amendment subsequent thereto reporting beneficial ownership of five percent or less of such class.) (See Rule 13d-7.) * The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). (Continued on the following page(s)) Page 1 of 5 Pages
<PAGE> Page 2 of 5 CUSIP NO. 375558103 (1) Names of Reporting Persons S.S. or I.R.S. Identification Nos. of Above Persons: First Union Corporation 56-0898180 (2) Check the Appropriate Box if a Member of a Group (See Instructions) (a) [ ] (b) [ ] (3) SEC Use Only (4) Citizenship or Place of Organization: North Carolina Number of Shares Beneficially Owned by Each Reporting Person with: (5) Sole Voting Power 0 (6) Shared Voting Power 0 (7) Sole Dispositive Power 0 (8) Shared Dispositive Power 0 (9) Aggregate Amount Beneficially Owned by Each Reporting Person 0 (10) Check if the Aggregate Amount in Row 9 Excludes Certain Shares (See Instructions) [ ] (11) Percent of Class Represented by Amount in Row 9 0.00 % (based on 29,734,000 shares outstanding on 12/31/97) (12) Type of Reporting Person (See Instructions) First Union Corporation (HC)
<PAGE> Page 3 of 5 Item 1(a) Name of Issuer: Gilead Sciences, Inc. Item 1(b) Address of Issuer's Principal Executive Offices: 333 Lakeside Drive Foster City, CA 94404 [X] Item 2(a) Name of Person Filing: First Union Corporation Item 2(b) Address of Principal Business Office: One First Union Center Charlotte, North Carolina 28288-0137 Item 2(c) Citizenship: North Carolina Item 2(d) Title of Class of Securities: Common Stock, Par Value $ .001 per share Item 2(e) CUSIP Number: 375558103 Item 3 If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b), check whether the person filing is a: (g)[X]Parent Holding Company, in accordance with section 240.13d-1(b) (ii) (G) Item 4 Ownership. (a)Amount Beneficially Owned: 0 (b)Percent of Class: 0.00% Number of shares as to which such person has: (i)sole power to vote or to direct the vote 0 (ii)shared power to vote or to direct the vote 0 (iii)sole power to dispose or to direct the disposition of 0 (iv)shared power to dispose or to direct the disposition of 0
<PAGE> Page 4 of 5 Item 5 Ownership of Five Percent or Less of a Class. Item 6 Ownership of More Than Five Percent on Behalf of Another Person. Not applicable Item 7 Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company. First Union Corporation is filing this schedule pursuant to Rule 13d-1(b)(ii)(G) as indicated under Item 3(g). Item 8 Identification and Classification of Members of the Group. Not applicable Item 9 Notice of Dissolution of Group. Not applicable Item 10 Certification. By signing below, I certify that, to the best of my knowledge and belief, the securities referred to above were acquired in the ordinary course of business and were not acquired for the purpose of and do not have the effect of changing or influencing the control of the issuer of such securities and were not acquired in connection with or as a participant in any transaction having such purposes or effect.
<PAGE> Page 5 of 5 Signature. After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. FIRST UNION CORPORATION February 11, 1998 Date Signature Karen F. Knudtsen, Assistant Vice President & Compliance Officer